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中华胃肠内镜电子杂志 ›› 2019, Vol. 06 ›› Issue (03) : 125 -129. doi: 10.3877/cma.j.issn.2095-7157.2019.03.007

所属专题: 文献

综述

他汀类药物在消化系统癌症中的使用研究进展
杨珍1, 虎金朋1, 牛敏1, 周燕1, 张玲2, 张雪2, 白飞虎3,()   
  1. 1. 750002 宁夏银川,宁夏医科大学第三临床医学院
    2. 750002 宁夏银川,西北民族大学第一临床医学院
    3. 750002 宁夏银川,宁夏人民医院消化内科
  • 收稿日期:2019-08-09 出版日期:2019-08-15
  • 通信作者: 白飞虎
  • 基金资助:
    国家自然科学基金项目(81760440); 中央引导地方科技发展专项(YDZX20176400004650); 宁夏消化疾病临床医学研究中心(2018CXPT0075)

Progress in the use of statins in cancers of the digestive system

Zhen Yang1, Jinpeng Hu1, Min Niu1, Yan Zhou1, Ling Zhang2, Xue Zhang2, Feihu Bai3,()   

  1. 1. Ningxia Medical University, Ningxia 750004, China
    2. Northwest Nationalities University First Clinical Medical College, Ningxia 750002, China
    3. People′s Hospital of Ningxia, Ningxia 750002, China
  • Received:2019-08-09 Published:2019-08-15
  • Corresponding author: Feihu Bai
  • About author:
    Corresponding author: Bai Feihu, Email:
引用本文:

杨珍, 虎金朋, 牛敏, 周燕, 张玲, 张雪, 白飞虎. 他汀类药物在消化系统癌症中的使用研究进展[J]. 中华胃肠内镜电子杂志, 2019, 06(03): 125-129.

Zhen Yang, Jinpeng Hu, Min Niu, Yan Zhou, Ling Zhang, Xue Zhang, Feihu Bai. Progress in the use of statins in cancers of the digestive system[J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2019, 06(03): 125-129.

随着经济的快速发展、人民饮食结构的改变及环境污染,消化系统癌症的发病率及死亡率呈逐年上升趋势,对于早期癌症可行内镜下治疗,进展期可采用外科手术、放疗、化疗、免疫治疗及靶向治疗等方法。近年来,多项研究显示,他汀类药物在消化系统癌症中的使用可一定程度上降低癌症患者的死亡率及患癌风险。本文主要探讨他汀类药物在消化系统癌症中的应用研究进展,有望为癌症的治疗发现新的辅助用药。

With the rapid development of the economy, the change of people's diet structure and environmental pollution, the incidence and mortality of cancer in the digestive system show an increasing trend. Surgery is the first choice in the early stage, and radiotherapy、chemotherapy、immunotherapy and targeted therapy can be adopted in the later stage. In recent years, several studies have shown that the use of statins in digestive cancer can reduce the mortality and cancer risk of cancer patients to some extent.This article mainly discusses that progress in the use of statins in cancers of the digestive system, which is expected to find new adjuvant drugs for the treatment of cancer.

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