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中华胃肠内镜电子杂志 ›› 2024, Vol. 11 ›› Issue (03) : 195 -199. doi: 10.3877/cma.j.issn.2095-7157.2024.03.011

综述

双联抗血小板药物对溃疡性结肠炎患者的影响及处理策略
黄锦1, 温静2,(), 李佳霖2, 韩丹2, 刘翠华2, 杨殿辉2, 张洋洋1   
  1. 1. 450000 郑州,联勤保障部队第988医院消化内科
    2. 100094 北京,联勤保障部队第984医院消化内科
  • 收稿日期:2024-03-26 出版日期:2024-08-15
  • 通信作者: 温静

The effect and management strategies of dual antiplatelet drugs on patients with ulcerative colitis

Jin Huang1, Jing Wen2,(), Jialin Li2, Dan Han2, Cuihua Liu2, Dianhui Yang2, Yangyang Zhang1   

  1. 1. Department of Gastroenterology, 988 Hospital of PLA Joint Logistics Support Force, Zhengzhou 450000, China
    2. Department of Gastroenterology and Hepatology, 984 Hospital of PLA Joint Logistics Support Force, Beijing 100094, China
  • Received:2024-03-26 Published:2024-08-15
  • Corresponding author: Jing Wen
引用本文:

黄锦, 温静, 李佳霖, 韩丹, 刘翠华, 杨殿辉, 张洋洋. 双联抗血小板药物对溃疡性结肠炎患者的影响及处理策略[J]. 中华胃肠内镜电子杂志, 2024, 11(03): 195-199.

Jin Huang, Jing Wen, Jialin Li, Dan Han, Cuihua Liu, Dianhui Yang, Yangyang Zhang. The effect and management strategies of dual antiplatelet drugs on patients with ulcerative colitis[J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2024, 11(03): 195-199.

溃疡性结肠炎患者存在血液高凝状态,常合并动脉粥样硬化性心血管疾病。因病变本身主要累及消化道,使用双联抗血小板治疗会增加患者消化道出血的风险,需权衡谨慎使用双联抗血小板治疗。本文就近十年来国内外文献关于抗血小板药物对溃疡性结肠炎患者的影响以及可能采取相关治疗措施进行总结。

Patients with ulcerative colitis have hypercoagulable blood and are often associated with atherosclerotic cardiovascular disease. Due to the fact that the lesion itself mainly affects the digestive tract, the use of dual antiplatelet therapy increases the risk of gastrointestinal bleeding in patients.Therefore, caution should be exercised when using dual antiplatelet therapy.This article presents a summary of the impact of antiplatelet drugs on patients with ulcerative colitis, as well as potential treatment measures, based on a review of domestic and foreign literature published over the past decade.

表1 临床常见的高缺血风险因素和高出血风险因素
表2 ARC-HBR定义的PCI高出血风险标准
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