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Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition) ›› 2019, Vol. 06 ›› Issue (02): 57-61. doi: 10.3877/cma.j.issn.2095-7157.2019.02.002

Special Issue:

• Original Article • Previous Articles     Next Articles

Analysis of risk factors for early rebleeding after endoscopic treatment of cirrhotic esophageal varices bleeding

Limei Ren1, Tong Dang1,(), Xianmei Meng1, Jing Wang1, Hongduo Pan1, Qihao Su1   

  1. 1. Department of Gastroenterology the Second Affiliated Hospital of Baotou Medical College, Baotou 014030, China
  • Received:2019-05-03 Online:2019-05-15 Published:2019-05-15
  • Contact: Tong Dang
  • About author:
    Corresponding author: Dang Tong, Email:

Abstract:

Objective

To explore the risk factors for endoscopic treatment of early rebleeding after rupture of esophageal varices (EVB) in patients with cirrhosis.

Method

Retrospective analysis of from August 2016 to Auguet 2018 patients with esophageal varices (EV) first bleeding in Second Affiliated Hospital of Baotou Medical College and the use of endoscopic treatment of patients. Patients with rebleeding within 6 weeks after surgery were divided into rebleeding group and non-bleeding group. Multivariate analysis was performed on the general data, liver function, blood routine, blood coagulation, portal vein thrombosis, and abnormal portal vein shunt in the two groups.Mirror treatment of risk factors for early rebleeding after esophageal varices.

Result

(1)A total of 450 patients were enrolled, and 27 patients had bleeding in the early stage (within 6 weeks) after treatment.The success rate of hemostasis was 94%.(2)Univariate analysis of AST(aspartate aminotransferase) GGT(γ-glutamyltransferase), TBIL(total bilirubin), ALB(albumin), PTA (prothrombin activity), The difference between TG (triglyceride), liver function Child-Pugh classification, esophageal varices, portal vein thrombosis, and portal vein abnormal shunt was statistically significant between the bleeding group and the non-bleeding group.(3)Multivariate logistic regression analysis showed that AST, GGT, PTA, TG, liver function Child-Pugh classification, esophageal varices, and portal vein thrombosis were the main risk factors for early rebleeding after esophageal varices(within 6 weeks). ALB and abnormal portal vein shunt were the main protective factors affecting early rebleeding after esophageal varices(P<0.05).

Conclusion

AST, GGT, PTA, TG, Child-Pugh classification of liver function, degree of esophageal varices, and portal vein thrombosis are the main risk factors for early rebleeding after esophageal varices(within 6 weeks); ALB and abnormal portal vein shunt are affecting esophagus the main protective factor for early rebleeding after varicose veins.

Key words: Esophageal varices, Early rebleeding, Endoscopic treatment, Abnormal portal vein shunt

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