Objective To develop expert consensus on the environment and layout of digestive endoscopy center.The overall layout, area partition and the configuration of medical equipment, protective equipment and fire facilities were designed according to the principle of "definite function, matched quantity, safe specification, reasonable layout". To avoid the risk of infection control and improve operation safety and patient satisfaction.

A compilation team was established to conduct article search on several databases such as China National Knowledge Infrastructure (CNKI) according to relevant domestic and foreign guidelines and consensus to screen and grade evidence.The preliminary draft of the consensus was completed, and was discussed through two rounds of expert demonstration meetings to carry out adjustment and modification before the consensus was developed.

The consensus suggest the digestive endoscopy center consist six functional area: appointment waiting area, diagnosis and treatment area, cleaning and disinfection area, resuscitation area, office and public living area and medical auxiliary area. The contents cover the layout and environmental requirements and standards of the relevant functional areas of the digestive endoscopy center, as well as how to do a good job in the relevant medical care of the digestive endoscopy center.

The consensus item is simple, clear and easy to implement. The new content can complement and improve the existing norms and standards to a certain extent. It can provide reference standards for new, rebuilt and expanded endoscopic diagnosis and treatment centers and guide clinical practice.

To explore the preliminary effect of endoscopic treatment of acute appendicitis based on the concept of super-minimally invasive technique.

The study was performed on 7 patients who underwent endoscopic therapy for acute appendicitis at Jiangsu Province Hospital of Chinese Medicine from September 2022 to May 2023.The methods of treatment, success rate, operation duration, hospital stay, complications, symptom remission and recurrence were analyzed retrospectively.

A total of 7 patients with acute appendicitis were collected, including 6 acute uncomplicated appendicitis: One case of impacted appendiceal fecalith incarceration underwent endoscopic appendiceal orifice myotomy and lithotomy; One case of appendix abscess was treated by drainage of pus and decompression with endoscopic appendiceal orifice myotomy; 4 patients with acute appendicitis underwent endoscopic retrograde appendicitis therapy (ERAT, including irrigation、stent placement、basket lithotomy), in one case, endoscopic retrograde appendiceal exploration and lavage were operated with the auxiliary eyeMax. One case of complicated appendicitis with peripheral abscess was treated with ERAT and stent drainage. The average procedure time was 30.43 min. Averagely, abdominal pain was relieved one day after the procedure, and all endoscopic treatments in these patients were successful. The average allowable feeding time after surgery was 2 days. The average post-operative hospital stay was 6.14 days. No recurrence occurred during 4 to 12 months′ follow-up, except the case with peripheral abscess undergoing elective surgical appendectomy.

Based on the super-minimally invasive concept, endoscopic minimally invasive treatment of acute appendicitis is safe and effective in various ways, but further controlled studies are needed.

This study aimed to investigate the hemostatic contribution of various endoscopic hemostasis methods in managing active hemorrhage caused by gastrointestinal malignancies.

In this study, we conducted a retrospective analysis of the medical records of patients who underwent endoscopic hemostasis to stop active bleeding in gastrointestinal malignancies at the First Medical Center of the PLA General Hospital between January 2001 and March 2022. Patients were divided into two groups based on the endoscopic hemostasis they received: the epinephrine-only group and the other endoscopic hemostatic treatments group, which included a combination with epinephrine.The primary outcome of this research was a comparison of the success rates of hemostasis between the two groups.

The study involved 65 individuals who had gastrointestinal malignancies with active bleeding.Of these, 34 were treated solely with epinephrine, while 31 received other endoscopic hemostatic treatments.The immediate hemostasis rates were 82.4% (28/34) and 100% (31/31), respectively, and the difference between the two groups was statistically significant (P=0.025). The endoscopic procedure durations were 17.5(12, 21) minutes and 22(14, 36) minutes for the two groups, respectively, with a statistically significant difference (P=0.020). The rates of rebleeding at 24 and 72 hours after endoscopic hemostasis were not significantly different between the two groups.

For the endoscopic management of gastrointestinal malignant active bleeding, electrocoagulation, mechanical hemostasis, cyanoacrylate injection, or a combination of these techniques with epinephrine are preferable than utilizing adrenaline alone.

To analyze the clinical and endoscopic characteristics of gastrointestinal telangiectasia of digestive tract, and evaluate the therapeutic effect of endoscopic treatment.

Follow-up and retrospective analysis was made on 229 patients who were diagnosed with telangiectasia after endoscopic examination in the Digestive Endoscopy Center of the Second Affiliated Hospital of Baotou Medical College from January 2019 to March 2022. Clinical characteristics and endoscopic treatment effects of those cases were analyzed.

Among the 229 patients, the male to female ratio was 1.34∶1, with an average age of 55.51 (29-87) years. The main telangiectasis sites in the upper digestive tract were gastric antrum and stomach body, the telangiectasia of the lower digestive tract was mainly in the whole colon and ileocecal junction. Fourteen patients received endoscopic treatment for gastrointestinal bleeding, 12 patients received electrocoagulation and hemostasis, 1 patient received radiofrequency ablation, and 1 patient received additional titanium clamp hemostasis after electrocoagulation and hemostasis. No postoperative complications occurred in the short term (7 days). In the long term (8 days-6 months), 1 patient developed hematochezia again.

Gastrointestinal telangiectasia tends to occur in the antrum of the stomach, most of which are single lesions. Endoscopic electrocoagulation and radiofrequency ablation are safe and effective in the treatment of gastrointestinal telangiectasia, with fewer intraoperative and postoperative complications and high overall survival rate.

This study aimed to provide a comprehensive overview of the current state of publications and research trends in the field of digestive endoscopic tunnel technique (DETT), both in China and internationally, from 2006 to the present.

A systematic search was conducted in the Web of Science and China National Knowledge Infrastructure databases to identify relevant literature of DETT published between January 1, 2006, and June 9, 2023. In order to analyze the hotspots of domestic and international research of DETT and to predict the future technological development, the characteristics of the included literature were extracted and analyzed using VOSviewer_1.6.18 software, which facilitated network visualization of journals, countries, institutions, authors, and keywords.

A total of 1, 333 English articles and 617 Chinese articles were included in the analysis. The number of publications in both Chinese and English has steadily increased since 2006, with a gradual decline in the past four years. Most publications were found in specialized journals in the field of endoscopy and gastroenterology.The United States, China, and Japan were the primary countries of publication, with Johns Hopkins University having the highest number of publications and Showa University having the highest number of citations per article.In terms of authors, Inoue Haruhiro had the most publications.Keyword clustering analysis revealed similar research trends in China and abroad. Peroral oral endoscopic myotomy (POEM) emerged as a prominent hotspot in submucosal endoscopy technology, with the most comprehensive clusters representing various applications of the technology.Overlay visualization demonstrated that endoscopy and natural orifice transluminal endoscopic surgery (NOTES) were foundational to the field, thereafter the emergence of POEM worked up to a climax. POEM-derived new techniques indicated the current and future directions of this field.

The research on DETT, both domestically and internationally, has experienced significant growth. This field has witnessed the emergence of various super minimally invasive diagnostic and therapeutic techniques. China has made substantial contributions to this field, with a high standard of vitality and advancement reaching international level.In the future, Chinese researchers should place emphasis on strengthening inter-regional and international collaborations.

Laparoscopic/robotic radical resection and super minimally invasive surgery(SMIS)are currently the main surgical methods for the treatment of gastric cancer.However, there are the following issues in clinical decision-making before and after surgery: (1)There is still a lack of effective means for accurately determining the scope of lymph node dissection in laparoscopic/robotic radical resection surgery; (2)There are still difficulties in accurately determining the presence of lymph node metastasis around the stomach after non-curative resection of super minimally invasive surgery.Currently, the use of the antigen-specific imaging agent ⁶⁸Ga-NC-BCH in combination with positron emission tomography-computed tomography (PET/CT) has shown promising results in guiding Chimeric Antigen Receptor T-Cell Immunotherapy (CART) treatment for gastric cancer patients. However, there is no relevant research on whether it can be combined with lymph node immune tracing to guide preoperative and postoperative clinical decisions for gastric cancer patients.Therefore, this study aims to explore the impact of ⁶⁸Ga-NC-BCH combined with PET-CT lymph node immune tracing on preoperative and postoperative clinical decisions for gastric cancer patients.

From April to September 2023, five cases of advanced gastric cancer patients who received treatment at the First Medical Center of PLA General Hospital were selected. Prior to surgery, abdominal CT scans and ⁶⁸Ga-NC-BCH combined PET-CT lymph node immune tracing were performed, followed by laparoscopic/robotic gastric cancer resection and extended lymph node dissection.

Among the 5 cases, preoperative CT scans indicated enlarged gastric lymph nodes in 3 cases (60%). However, lymph node immunostaining using ⁶⁸Ga-NC-BCH combined with PET-CT did not reveal any abnormalities. Postoperative pathological examination of the enlarged lymph nodes confirmed the absence of cancer tissue in all 3 cases.The results of preoperative lymph node immunostaining using ⁶⁸Ga-NC-BCH combined with PET-CT were consistent with postoperative pathological examination results in all 5 cases (100%). These preliminary findings suggest that compared to CT, lymph node immunostaining using ⁶⁸Ga-NC-BCH combined with PET-CT has higher accuracy in determining gastric lymph node metastasis in patients with gastric cancer.

This study preliminarily confirmed the feasibility and safety of using ⁶⁸Ga-NC-BCH combined with PET-CT lymph node immune tracing to guide preoperative and postoperative clinical decisions for gastric cancer patients. However, further prospective studies with larger sample sizes are needed to confirm the above conclusion.

To study the clinical characteristics of children swallowing magnetic digestive tract foreign bodies by mistake and analyze the risk factors, so as to seek effective preventive measures and optimize the treatment plan.

Retrospective analysis was performed on the case data of children hospitalized for swallowing magnetic foreign bodies by mistake in Xi 'an Children's Hospital from January 2015 to December 2021.

Among the 153 cases of children who mistakenly swallowed magnetic foreign bodies, most of them were male (68.6%), mostly in early childhood and early school age, and the age fluctuated from 6 months to 14 years old.The number of hospitalizations and the number of surgical operations showed an increasing trend year by year.The number of mistakenly swallowed magnetic foreign bodies varied (1-60), and the types of foreign bodies were different. 85% of patients mistakenly swallowed multiple magnetic foreign bodies or magnetic foreign bodies combined with metal foreign bodies.Eighty-five patients(55.6%) underwent surgical intervention, and the main clinical symptoms were abdominal pain, among which 81 patients had digestive tract fistula, and entero-enteric fistula was the most common (50.6%). compared with the low age group, the OR value of complications in the high age group was 2.280 (95%CI: 1.155-4.501); Compared with other types of foreign bodies, the OR of buckball complications caused by swallowing magnetic beads by mistake was 30.816(95%CI: 7.291-130.254). The presence of clinical symptoms and the time of treatment >1 day significantly increased the risk of complications (P<0.05).

Swallowing magnetic foreign bodies can easily cause serious complications such as digestive tract perforation, thus early detection, diagnosis and treatment are particularly important. Emergency gastroscopy within 24 hours after misingestion is the preferred treatment. If the location of magnetic foreign bodies on X-ray is not moved after multiple dynamic monitoring for more than 24 hours, surgery should be performed in time if there are clinical symptoms.In addition, comprehensive preventive measures should also be taken by age group and multiple parties to reduce the incidence.

To compare the value of multi-target fecal DNA detection and PuPu Tube self-administered fecal immunochemical test (PuPu tube FIT) in colorectal cancer screening in physical examination population.

From January 2020 to December 2020, asymptomatic people who underwent physical examination in the Physical Examination Center of China Aerospace Science and Industry Corporation 731 Hospital were selected.Multi-target fecal DNA detection and PuPu tube FIT were used for primary screening.Colonoscopy was performed for those who were positive, and the screening results were analyzed and summarized.

A total of 660 subjects completed multi-target fecal DNA detection andPuPu tube FIT, of which 42 cases were positive for multi-target fecal DNA detection, 55 cases were positive for PuPu tube FIT detection.The detection rate of colorectal cancer and advanced adenoma was 1.36% and the positive predictive value was 32.14% for those with positive multi-target fecal DNA detection. The detection rate of colorectal cancer and advanced adenoma was 0.30% and the positive predictive value was 7.69% for those with positive PuPu tube FIT detection, and the detection rate and positive predictive value of colorectal cancer and advanced adenoma by multi-target fecal DNA detection were higher than those by PuPu tube FIT, and the differences were statistically significant (P<0.05).

Compared with PuPu tube FIT, multi- target fecal DNA detection has higher detection rate and positive predictive value for colorectal cancer and advanced adenoma. Therefore, multi-target fecal DNA detection has a higher screening value for colorectal cancer in physical examination population.

To retrospectively analyze the safety and efficacy of conventional-endoscopic mucosal resection(c-EMR), modified-endoscopic mucosal resection (m-EMR) and endoscopic submucosal dissection (ESD) in the treatment of <10 mm and ≥10 mm rectal neuroendocrine tumor (R-NEN).

The total of 120 patients with R-NEN confirmed by postoperative pathological results who receive treatment in the Gastrointestinal Center of Northern Jiangsu People′s Hospital from May 2012 to May 2022 were selected as the study subjects. We retrospectively analyzed the en bloc resection rate, histological complete resection, operative complication, and time of different endoscopic procedures.

A total of 120 patients were included, of which 24 underwent c-EMR, 30 underwent m-EMR and 66 underwent ESD.There were 79 patients in the diameter<10 mm group, 16 patients underwent c-EMR, 18 patients underwent m-EMR, 45 patients underwent ESD. There were no significant differences in the en bloc resection rate and histological complete resection among the three groups (P>0.05). There were 41 patients in the diameter ≥10 mm group, 8 patients underwent c-EMR, 12 patients underwent m-EMR, 21 patients underwent ESD. The histological resection rate of m-EMR and ESD group was higher than that of c-EMR group, and the difference was statistically significant (P<0.05). The operation time of c-EMR and m-EMR group was shorter than that of ESD group among patients in the diameter <10 mm group and ≥10 mm group.

C-EMR, m-EMR and ESD can effectively and safely resect R-NEN with tumor diameter <10mm, but m-EMR and ESD are recommended for ≥10 mm tumors. Follow-up is still important no matter which endoscopic procedure was chosen.