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Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition) ›› 2021, Vol. 08 ›› Issue (01): 18-23. doi: 10.3877/cma.j.issn.2095-7157.2021.01.003

Special Issue:

• Original Article • Previous Articles     Next Articles

Meta-analysis of the efficacy comparison of retrograde endoscopic appendicitis in the treatment of acute non-perforated appendicitis

lin Liu1, Shuquan Duan2,(), Xianmei Meng1, Tong Dang1,()   

  1. 1. Department of Gastroenterology, Second Affiliated Hospital of Baotou Medical College, Baotou 014030, China
    2. Department of Minimally Invasive Digestive Center, Second Affiliated Hospital of Baotou Medical College, Baotou 014030, China
  • Received:2020-04-10 Online:2021-02-15 Published:2021-03-23
  • Contact: Shuquan Duan, Tong Dang

Abstract:

Objective

To explore the feasibility of endoscopic retrograde appendicitis in the treatment of acute non-perforated appendicitis.

Method

Retrieve the pubmed、cochrane Library Control Test Registration Database, Chinese Journal full text Database, Wanfang Database, Weipu Database, from January 2012 to April 2019 related literature on endoscopic retrograde appendicitis and laparoscopic surgery for acute non-perforated appendicitis, the Cochrane collaboration with Rev Man 5.3 edition software for statistical processing, analyze the heterogeneity in data, calculate the OR value OR MD and its 95% confidence interval.

Results

16 clinical studies with a total of 1375 patients were enrolled according to the inclusion criteria.Meta analysis showed that endoscopic retrograde appendicitis treatment and laparoscopic surgery for acute non-perforated appendicitis compared the curative effect, endoscopic retrograde appendicitis treatment of shorter hospital stay MD(95%CI)= -2.46(-2.93, -1.99), P<0.05, Lower incidence of complications OR (95%CI) =0.23(0.16 0.33), P<0.05, Short operation time MD(95%CI)=-19.89(-21.8, -17.93), P<0.05, and Postoperative recovery was faster MD(95%CI)= -3.16(-4.13, -2.19), P<0.05.

Conclusions

the results of meta-analysis suggest that endoscopic retrograde appendicitis is a safe and feasible method for the treatment of acute non-perforatedre appendicitis, which has many advantages, such as short operation time, short hospitalization time, rapid recovery of patients, fewer complications, and good cosmetic effect, However, at present, this treatment method is not completely popular, and this conclusion needs to be confirmed by large-scale clinical data.

Key words: Endoscopic retrograde appendicitis therapy, laparoscopic surgery, Acute non-perforated appendicitis, Meta-analysis

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