Research progress on the role and mechanism of circular RNA in gastrointestinal stromal tumors

doi:10.3877/cma.j.issn.2095-7157.2021.04.007

Abstract

Abstract:

Gastrointestinal stromal tumor originates from interstitial cells of Cajal, and its morbidity and mortality is higher. CircRNA is a new type of special non-coding RNA, which has a covalent closed loop structure without a 5′cap or 3′poly A tail, and can encode a small amount of polypeptides. The latest research shows that circRNA is involved in multiple biological processes such as proliferation, invasion and metastasis in the occurrence of gastrointestinal stromal tumors, and the clinical and pathological characteristics of patients are closely related to the expression level of circRNA. Further research on the role and mechanism of circRNA in gastrointestinal stromal tumors will provide new directions for its clinical diagnosis and treatment.

Key words: circRNA, Gastrointestinal stromal tumor, Research progress, Reviews

Chunyan Zou, Dongqiang Zhao. Research progress on the role and mechanism of circular RNA in gastrointestinal stromal tumors[J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2021, 08(04): 179-181.

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https://zhwcnjdzzz.cma-cmc.com.cn/EN/Y2021/V08/I04/179

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