To evaluate the changes in quality of life and psychological status in patients with colorectal cancer under the super minimally invasive surgery(SMIS) mode or the organ resection mode.

Prospectively, patients with colorectal cancer who were hospitalized in the First Medical Center of Chinese PLA General Hospital from March to August 2023 were included.The patients were divided into two groups according to whether intestinal resection was performed during the operation: SMIS group(simple excision of the lesion to preserve the intestinal tract) and organ resection group(excision of part of the intestine along with the lesion).Prior to surgery and postoperatively at 1, 3, and 6 months, data on the patient′s quality of life and psychological state were collected.The quality of life was assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 and-CR29, and the psychological status was evaluated using the Fear of Progression Questionnaire-Short Form (FoP-Q-SF), Self-rating anxiety scale (SAS), and Self-rating depression scale (SDS).

A total of 47 patients were included in the study, with 24 in the SMIS group and 23 in the organ resection group.In the SMIS group, the scores for blood or mucus in stool, stool frequency and FoP-Q-SF at the postoperative 1st, 3rd and 6th month were significantly lower than those before operation.Physical fitness, role function, social function, and blood or mucus in stools scores were lower than the preoperative levels in the organ resection group at 1 month postoperatively; while fatigue, pain, dyspnea, buttock pain, taste abnormalities, flatulence, fecal incontinence, skin pain and defecation embarrassment scores were higher than preoperative levels.In the organ resection group, the postoperative 3rd and 6th month scores for blood or mucus in stool were lower than the preoperative level; the score for defecation embarrassment was higher than the preoperative level; however, there were no significant differences in FoP-Q-SF, SAS and SDS compared with the preoperative period.

Under the SMIS mode, the quality of life and fear of disease progression in psychological status for colorectal cancer patients improved at 1, 3, and 6 months postoperatively compared to the preoperative period. Under the organ resection mode, the quality of life significantly declined at 1 month postoperatively, then gradually improved within 3 to 6 months, with no significant changes in psychological status.