Recurrent gastrointestinal bleeding caused by Brunner′s adenohamartoma of duodenum: a case report and literature review

doi:10.3877/cma.j.issn.2095-7157.2024.03.008

Abstract

Abstract:

Objective

Brunner′s gland hamartoma of duodenum is a rare disease, with a high misdiagnosis rate before operation. This paper reports the diagnosis and treatment of a case of BGH with recurrent gastrointestinal bleeding, and summarizes the characteristics of this disease in combination with previous literature in order to provide reference for clinical work.

Methods

The clinical data of a patient with BGH admitted to the Department of Gastroenterology, PLA Rocket Forces Characteristic Medical Center were analyzed and 81 cases reported in recent 10 years were summarized.

Results

The patient in this center underwent endoscopic resection of a 4.5 cm×3 cm×1.8 cm duodenal tumor due to repeated black stool, and the pathological diagnosis was hamartomatous polyp. The cases reported in the literature mainly showed abdominal pain, melena, nausea and vomiting, and anemia. 89.19% of the tumors were over 2 cm in size, and the percentage of chose of surgery, endoscopic resection and conservative treatment was 53.09%, 41.98% and 3.70% respectively.

Conclusion

BGH is easy to be misdiagnosed and should be considered in the differential diagnosis of duodenal submucosal tumor or gastrointestinal bleeding.

Key words: Submucosal tumor of duodenum, Hamartoma, Gastrointestinal bleeding

Liya Li, Dan Zhang, Jijuan Zhang, Changzheng Li, Xiaobing Ma, Meng Li, Tian Tian. Recurrent gastrointestinal bleeding caused by Brunner′s adenohamartoma of duodenum: a case report and literature review[J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2024, 11(03): 182-185.

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References 22

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作者	发表年份(年)	性别	年龄(岁)	临床症状	初诊疾病
Kostalas等^[9]	2016	女	52	消瘦	胆道梗阻
Huo等^[11]	2016	女	58	腹痛、恶心呕吐	胃肠道间质瘤
Ramay等^[21]	2018	女	84	贫血	十二指肠息肉
Gupta等^[7]	2019	男	43	梗阻、腹痛	胰腺炎、幽门梗阻
秦榕等^[19]	2019	男	19	黑便	十二指肠肿物
		男	54	腹痛	十二指肠肿物
		女	60	恶心呕吐	十二指肠肿物
Bakir等^[1]	2020	男	57	呕血、呕吐、消瘦	十二指肠息肉、幽门梗阻
Dhali等^[8]	2021	女	44	黑便、呕血、腹痛、呕吐	十二指肠息肉
徐家军等^[16]	2022	男	75	消瘦、乏力	十二指肠脂肪瘤
吴叶凡等^[22]	2024	女	56	腹痛	十二指肠肿物、肝内外胆管、胰管轻度扩张
Duan等^[13]	2024	女	31	黑便、乏力	十二指肠黏膜下隆起

作者	发表年份(年)	性别	年龄(岁)	临床症状	初诊疾病
Kostalas等^[9]	2016	女	52	消瘦	胆道梗阻
Huo等^[11]	2016	女	58	腹痛、恶心呕吐	胃肠道间质瘤
Ramay等^[21]	2018	女	84	贫血	十二指肠息肉
Gupta等^[7]	2019	男	43	梗阻、腹痛	胰腺炎、幽门梗阻
秦榕等^[19]	2019	男	19	黑便	十二指肠肿物
		男	54	腹痛	十二指肠肿物
		女	60	恶心呕吐	十二指肠肿物
Bakir等^[1]	2020	男	57	呕血、呕吐、消瘦	十二指肠息肉、幽门梗阻
Dhali等^[8]	2021	女	44	黑便、呕血、腹痛、呕吐	十二指肠息肉
徐家军等^[16]	2022	男	75	消瘦、乏力	十二指肠脂肪瘤
吴叶凡等^[22]	2024	女	56	腹痛	十二指肠肿物、肝内外胆管、胰管轻度扩张
Duan等^[13]	2024	女	31	黑便、乏力	十二指肠黏膜下隆起

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