硬化疗法作为目前食管静脉曲张(EV)的主要手段之一，其临床效果已被医务工作者所认可。目前我国常用的硬化疗法，多采用聚桂醇或组织胶局部注射的方法，通过局部血管的坏死、脱落和溃疡形成来达到消除曲张静脉的效果，存在食管曲张静脉消除不充分、复发率高、并发症多的缺点。日本针对EV的治疗多采用透视下三步硬化疗法，EV的消除较为充分，同时复发率及并发症较少。本文拟对EV治疗的透视下三步硬化疗法的具体操作过程进行详细介绍，推动其在中国的应用。

Sclerotherapy is one of the primary means of esophageal varices, the clinical effect of which has been recognized by medical workers.At present, the commonly used sclerotherapy in our country mostly adopts the method of local injection of lauromacrogol or tissue glue to achieve the effect of eliminating varicose veins through the formation of necrosis, shedding and ulceration of local blood vessels. The biggest drawback is the inadequate elimination of esophageal varicose veins, high recurrence rate, more complications. For the treatment of esophageal varices in Japan, the doctors often use the fluoroscopic three-step sclerotherapy, the elimination of esophageal varices is more adequate, while less recurrence and complications. The article intends to introduce the operation the fluoroscopic three-step sclerotherapy for esophageal varices, in order to promote its application in China.