Advances in oligopeptides absorption

doi:10.3877/cma.j.issn.2095-7157.2018.04.006

Abstract

Abstract:

Proteins can be digested into free amino acids and oligopeptides by various enzymes in the gastrointestinal tract. It has been recognized that oligopeptides, especially small peptides, can be directly absorbed and utilized by animals since the 1960s. The oligopeptides can be absorbed by small intestinal epithelial cells through paracellular pathway, passive diffusion, endocytosis or carrier transport. Its biological activity also has a wide application prospect in oral drug delivery. The main influencing factors are feeding level, protein quality, length of peptide chain, configuration of amino acid residues, carrier and animal health status, etc..

Key words: Oligopeptides, Absorption mechanism, Influencing factors

Ning Wang, Enqiang Linghu. Advances in oligopeptides absorption[J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2018, 05(04): 167-173.

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