Application value of an in-vivo porcine model in the training of advanced endoscopic therapy

doi:10.3877/cma.j.issn.2095-7157.2022.03.009

Abstract

Abstract:

Objective

To further confirm and clarify its application value in the training of advanced endoscopic therapy through an in-vivo porcine model.

Methods

6 trainees were selected to receive in-vivo porcine model training, and then 6 trainees and 6 controls were given hand-to-hand training. Then, the differences between trainees receiving live pig model and hand-held training, as well as the differences between trainees and controls regarding whether to receive live pig model training were compared.

Results

There was no intraoperative hemorrhage and delayed postoperative hemorrhage in all the in-vivo porcine models and hand-to-hand training operations. There were 2 cases of local minor perforation in each training operation, which could be effectively closed by tissue clip, and no delayed postoperative perforation.No other serious complications occurred in all experimental animals and patients.All the operations were completely dissection of the lesions, only a few of them needed to be completed by superior teaching physicians. After receiving in-vivo porcine model training, the dissection time and speed of the trainees were significantly improved (P< 0.05). Compared with the control group, the operation time (including the time of each step), dissection speed, operation completion score, injection score and incision score of the trainees were significantly improved (P< 0.05).

Conclusion

The in-vivo porcine model is safe and effective for the training of advanced endoscopic therapies. It is helpful to improve the learning curve of beginners and effectively deal with complications.

Key words: In-vivo porcine model, Advanced endoscopic therapy, Learning curve, Safety

Nanjun Wang, Ningli Chai, Enqiang Linghu, Huikai Li, Xiuxue Feng, Yaqi Zhai, Shengzhen Liu, Wengang Zhang, Longsong Li, Shasha Wang, Xiangyao Wang, Ning Xu, Fei Gao. Application value of an in-vivo porcine model in the training of advanced endoscopic therapy[J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2022, 09(03): 156-161.

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URL: https://zhwcnjdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-7157.2022.03.009

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References 22

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项目		受训者	对照者	P值
内镜年限(年)		5.23±1.50	5.27±1.70	0.972
胃肠镜数(例)		5 231.5 (914.75)	5 505 (1 152.5)	0.699
手术时间(min)		46(22.5)	67(34.25)	0.001
	注射时间	7.67±2.96	9.23±2.21	0.024
	切开时间	9.5(5.25)	15(5.25)	0.001
	剥离时间	24.5(12)	33.5(23.25)	0.006
	止血时间	5(2)	7(5)	0.002
标本面积(cm²)		8.80±2.69	8.47±2.36	0.621
剥离速度(cm²/min)		0.17(0.0225)	0.12(0.0125)	<0.001
手术完成度评分		3(1)	3(1)	0.004
	注射评分	3(1)	2(1)	<0.001
	切开评分	3(1)	3(1)	0.001
	剥离评分	3(2)	2.5(1)	0.176
	止血评分	3(1)	3(0.25)	0.100

项目		受训者	对照者	P值
内镜年限(年)		5.23±1.50	5.27±1.70	0.972
胃肠镜数(例)		5 231.5 (914.75)	5 505 (1 152.5)	0.699
手术时间(min)		46(22.5)	67(34.25)	0.001
	注射时间	7.67±2.96	9.23±2.21	0.024
	切开时间	9.5(5.25)	15(5.25)	0.001
	剥离时间	24.5(12)	33.5(23.25)	0.006
	止血时间	5(2)	7(5)	0.002
标本面积(cm²)		8.80±2.69	8.47±2.36	0.621
剥离速度(cm²/min)		0.17(0.0225)	0.12(0.0125)	<0.001
手术完成度评分		3(1)	3(1)	0.004
	注射评分	3(1)	2(1)	<0.001
	切开评分	3(1)	3(1)	0.001
	剥离评分	3(2)	2.5(1)	0.176
	止血评分	3(1)	3(0.25)	0.100

项目		活体猪培训	手把手带教	P值
手术时间(min)		64.50±17.05	51.00±16.34	0.060
	注射时间	11.92±3.99	9.33±3.23	0.095
	切开时间	14(6.75)	8.5(3.75)	0.160
	剥离时间	33.42±8.30	26.50±7.24	0.041
	止血时间	6.92±1.93	5.67±2.19	0.152
标本面积(cm²)		8.59±2.44	9.00±2.96	0.716
剥离速度(cm²/min)		0.13±0.014	0.18±0.016	<0.001
手术完成度评分		3(0.75)	3(1)	0.291
	注射评分	3(0)	4(1)	0.089
	切开评分	3(2)	4(1)	0.198
	剥离评分	2(1)	3(2)	0.114
	止血评分	3(2)	3(2)	0.799

项目		活体猪培训	手把手带教	P值
手术时间(min)		64.50±17.05	51.00±16.34	0.060
	注射时间	11.92±3.99	9.33±3.23	0.095
	切开时间	14(6.75)	8.5(3.75)	0.160
	剥离时间	33.42±8.30	26.50±7.24	0.041
	止血时间	6.92±1.93	5.67±2.19	0.152
标本面积(cm²)		8.59±2.44	9.00±2.96	0.716
剥离速度(cm²/min)		0.13±0.014	0.18±0.016	<0.001
手术完成度评分		3(0.75)	3(1)	0.291
	注射评分	3(0)	4(1)	0.089
	切开评分	3(2)	4(1)	0.198
	剥离评分	2(1)	3(2)	0.114
	止血评分	3(2)	3(2)	0.799

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