Clinical study on the management of patients with recurrent gastric low-grade intraepithelial neoplasia after endoscopic radiofrequency ablation

doi:10.3877/cma.j.issn.2095-7157.2022.04.003

Abstract

Abstract:

Objective

To explore the clinical management strategy of patients with recurrent gastric low-grade intraepithelial neoplasia after radiofrequency ablation.

Methods

53 patients with recurrent gastric low-grade intraepithelial neoplasia who completed radiofrequency ablation in our center from October 2014 to September 2022 were retrospectively selected and divided into follow-up group and treatment group according to whether they received additional treatment. The relevant indicators of the two groups were compared and analyzed.

Results

There were no significant differences in gender, age, course of disease, site of lesion and duration of follow-up between the two groups (P> 0.05), but the elimination rate of lesion in the treatment group was significantly better than that in the follow-up group (91.3% vs 43.3%, P< 0.001). However, there was no significant difference between the three surgical methods in the treatment group (P= 0.640).

Conclusion

Additional endoscopic ablation or resection is recommended for patients with recurrent gastric low-grade intraepithelial neoplasia after radiofrequency ablation.

Key words: Gastric low-grade intraepithelial neoplasia, Endoscopic radiofrequency ablation, Recurrence

Nanjun Wang, Ningli Chai, Enqiang Linghu, Xiaotong Niu, Shengzhen Liu, Longsong Li, Wengang Zhang, Shasha Wang, Fei Gao. Clinical study on the management of patients with recurrent gastric low-grade intraepithelial neoplasia after endoscopic radiofrequency ablation[J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2022, 09(04): 207-211.

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URL: https://zhwcnjdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-7157.2022.04.003

https://zhwcnjdzzz.cma-cmc.com.cn/EN/Y2022/V09/I04/207

Figures/Tables 6

References 19

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项目		随访组(n＝30)	治疗组(n＝23)	P值
性别				0.061
	男	16(53.3)	18(78.3)
	女	14(46.7)	5(21.7)
年龄(岁)		58.2±9.1	60.0±7.5	0.454
病程(月)		21.8±11.2	19.0±11.3	0.374
病变部位				1.000
	胃底(含贲门)~胃体	2(6.7)	1(4.3)
	胃角	11(36.7)	8(34.8)
	胃窦(含幽门)	17(56.7)	14(60.9)
随访时长(月)		28.8±22.0	25.4±17.7	0.547
病变是否消退				<0.001
	是	13(43.3)	21(91.3)
	否	17(56.7)	2(8.7)

项目		随访组(n＝30)	治疗组(n＝23)	P值
性别				0.061
	男	16(53.3)	18(78.3)
	女	14(46.7)	5(21.7)
年龄(岁)		58.2±9.1	60.0±7.5	0.454
病程(月)		21.8±11.2	19.0±11.3	0.374
病变部位				1.000
	胃底(含贲门)~胃体	2(6.7)	1(4.3)
	胃角	11(36.7)	8(34.8)
	胃窦(含幽门)	17(56.7)	14(60.9)
随访时长(月)		28.8±22.0	25.4±17.7	0.547
病变是否消退				<0.001
	是	13(43.3)	21(91.3)
	否	17(56.7)	2(8.7)

治疗方法	病变消退(n＝21)	病变未消退(n＝2)
RFA	13(61.9)	1(50)
APC	4(19)	1(50)
ESD	4(19)	0
P值	0.640

治疗方法	病变消退(n＝21)	病变未消退(n＝2)
RFA	13(61.9)	1(50)
APC	4(19)	1(50)
ESD	4(19)	0
P值	0.640

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