The clinical study of endoscopic radiofrequency ablation in the treatment of gastric low-grade intraepithelial neoplasia

doi:10.3877/cma.j.issn.2095-7157.2020.03.003

Abstract

Abstract:

Objective

To evaluate the curative effect and security of endoscopic radiofrequency ablation(RFA) in the treatment of gastric low-grade intraepithelial neoplasia(LGIN) through a large clinical sample study.

Methods

We conducted a clinical study of 255 cases of gastric LGIN undergoing RFA with complete data in our Digestive endoscopy center between October 2014 and December 2019, pay close attention to the perioperative complications and the follow-up results, using the Wong-Baker scoring scale to evaluate the postoperative pain.

Results

Endoscopic RFA was successfully performed in all the 255 cases, and no obvious complications occurred during the operation.The cure rates after 3 months, 6 months, 1 year, 2 years and 3 years were 91.3%, 90.8%, 89.4%, 88.2% and 86.5%, respectively, and abdominal pain was the main postoperative complication.

Conclusions

Endoscopic RFA is a safe, effective, simple and outpatient treatment for gastric LGIN. It has a promising clinical application prospect.

Key words: Endoscopic radiofrequency ablation, Gastric low-grade intraepithelial neoplasia, Curative effect, Safety

Nanjun Wang, Ningli Chai, Enqiang Linghu, Jia Feng, Huikai Li, Yaqi Zhai, Xiuxue Feng, Zantao Wang, Wengang Zhang, Longsong Li, Shasha Wang, Lisen Zhong, Fei Gao. The clinical study of endoscopic radiofrequency ablation in the treatment of gastric low-grade intraepithelial neoplasia[J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2020, 07(03): 117-120.

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URL: https://zhwcnjdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-7157.2020.03.003

https://zhwcnjdzzz.cma-cmc.com.cn/EN/Y2020/V07/I03/117

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References 14

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观察指标		例数	百分比(%)
病变部位		?	?
?	胃底(含贲门)	6	2.4
?	胃体	23	9.0
?	胃角	57	22.4
?	胃窦(含幽门)	169	66.3
病变内镜下表现		?	?
?	0-IIa型	86	33.7
?	0-IIb型	162	63.5
?	0-IIc型	7	2.7
病变数量		?	?
?	1处	118	67.4
?	2处	38	21.7
?	3处	15	8.6
?	4处	4	2.3

观察指标		例数	百分比(%)
病变部位		?	?
?	胃底(含贲门)	6	2.4
?	胃体	23	9.0
?	胃角	57	22.4
?	胃窦(含幽门)	169	66.3
病变内镜下表现		?	?
?	0-IIa型	86	33.7
?	0-IIb型	162	63.5
?	0-IIc型	7	2.7
病变数量		?	?
?	1处	118	67.4
?	2处	38	21.7
?	3处	15	8.6
?	4处	4	2.3

随访期限	例数	治愈	复发	再发	进展
3月	184	168(91.3)	14(7.6)	14(7.6)	2(1.1)
6月	130	118(90.8)	12(9.2)	5(3.8)	0
1年	94	84(89.4)	10(10.6)	11(11.7)	0
2年	68	60(88.2)	8(11.8)	4(5.9)	0
3年	52	45(86.5)	5(9.6)	6(11.5)	2(3.8)
4年	21	20	1	3	0
5年	2	1	1	0	0

随访期限	例数	治愈	复发	再发	进展
3月	184	168(91.3)	14(7.6)	14(7.6)	2(1.1)
6月	130	118(90.8)	12(9.2)	5(3.8)	0
1年	94	84(89.4)	10(10.6)	11(11.7)	0
2年	68	60(88.2)	8(11.8)	4(5.9)	0
3年	52	45(86.5)	5(9.6)	6(11.5)	2(3.8)
4年	21	20	1	3	0
5年	2	1	1	0	0

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