Analysis of the value of serum pepsinogen, gastrin-17, and Helicobacter pylori antibody detection in screening gastric cancer risk groups

doi:10.3877/cma.j.issn.2095-7157.2021.01.007

Abstract

Abstract:

Gastric cancer is one of the most common malignant tumors of the digestive tract, with a high mortality rate. Early diagnosis and treatment is of great significance to patients with gastric cancer. Serum molecular markers play an important role in the screening and prognostic evaluation of gastric cancer and precancerous diseases due to their advantages of low cost, simple and easy operation, little pain, and dynamic monitoring, and are widely used in clinical applications at home and abroad.This article reviews the value of serum pepsinogengastrin-17, and Helicobacter pylori antibody detection in screening gastric cancer risk groups.

Key words: Gastric cancer, Mass screening, Pepsinogen, Gastrin-17, Helicobacter pylori antibody

Weiyu Liu, Xiaozhong Gao. Analysis of the value of serum pepsinogen, gastrin-17, and Helicobacter pylori antibody detection in screening gastric cancer risk groups[J]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2021, 08(01): 37-41.

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References 37

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项目	PG Ⅰ	PG Ⅱ	PGR	G-17	抗Hp-IgG抗体
正常胃黏膜	N	N	N	N	-
萎缩性胃炎(胃窦为主)	↓	N	↓	↓	＋
萎缩性胃炎(胃体为主)	↓	N	↓	↑	＋/-
多病灶萎缩性胃炎	↓	N/↓	↓	↓	＋
胃癌	↓	N/↓	↓	N/↓	＋/-

项目	PG Ⅰ	PG Ⅱ	PGR	G-17	抗Hp-IgG抗体
正常胃黏膜	N	N	N	N	-
萎缩性胃炎(胃窦为主)	↓	N	↓	↓	＋
萎缩性胃炎(胃体为主)	↓	N	↓	↑	＋/-
多病灶萎缩性胃炎	↓	N/↓	↓	↓	＋
胃癌	↓	N/↓	↓	N/↓	＋/-

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