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中华胃肠内镜电子杂志 ›› 2026, Vol. 13 ›› Issue (01) : 5 -9. doi: 10.3877/cma.j.issn.2095-7157.2026.01.002

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基于超级微创手术理论再看人体生命观的解构与重建
令狐恩强()   
  1. 100853 北京,解放军总医院第一医学中心消化内科医学部
  • 收稿日期:2026-01-17 出版日期:2026-02-15
  • 通信作者: 令狐恩强
  • 基金资助:
    十四五国家重点研发计划(2022YFC2503600)

Deconstruction and reconstruction of the human life view from the perspective of super minimally invasive surgery (SMIS) theory

Enqiang Linghu()   

  1. Department of Gastroenterology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China
  • Received:2026-01-17 Published:2026-02-15
  • Corresponding author: Enqiang Linghu
引用本文:

令狐恩强. 基于超级微创手术理论再看人体生命观的解构与重建[J/OL]. 中华胃肠内镜电子杂志, 2026, 13(01): 5-9.

Enqiang Linghu. Deconstruction and reconstruction of the human life view from the perspective of super minimally invasive surgery (SMIS) theory[J/OL]. Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition), 2026, 13(01): 5-9.

现代医学正经历从机械还原论到有机整体论的深刻范式转变。本文旨在解构以大脑为中心、将人体视为"精密机器"的传统生命观,重建一种基于"器官联邦"模型的分布式生命观,并以此为哲学与科学基石,系统阐述超级微创手术(SMIS)的基本理论。我们提出,人体是由众多具备记忆、再生、适应与内在节律等自主智慧的"准生命体"器官构成的协作联邦。高级神经中枢通过精妙的"整合与遮蔽"机制,将这些自主性统一为连贯的个体意识与行为。SMIS理论正是根植于对这种器官固有生命潜能的深刻尊重。其核心在于,医疗干预应从传统的"病变切除"逻辑,转向以极致化保全器官结构与功能完整性为目标的"调控与支持"逻辑。本文将从器官自主性的科学证据、高层控制的遮蔽机制、控制失效后的生命连续性启示以及对外科范式的重塑四个方面,论证这一新生命观如何为SMIS提供根本性的理论依据,并指引手术学向以功能保全为核心的方向演进。

Modern medicine is undergoing a profound paradigm shift from mechanical reductionism to organic holism.This article aims to deconstruct the traditional view of life, which is brain-centered and regards the human body as a "precise machine", and to reconstruct a distributed view of life based on the "organ federation" model.Using this as the philosophical and scientific cornerstone, it systematically elaborates the fundamental principles of super minimally invasive surgery (SMIS). We propose that the human body is a collaborative federation composed of numerous "quasi-living" organs possessing autonomous intelligence such as memory, regeneration, adaptation, and intrinsic rhythms.The advanced neural centers unify these autonomies into coherent individual consciousness and behavior through an exquisite mechanism of "integration and obscuration". The principle of SMIS is rooted precisely in a profound respect for this inherent life potential of organs.Its core lies in shifting medical intervention from the traditional logic of "lesion resection" to a "regulation and support" logic aimed at maximally preserving the structural and functional integrity of organs.This article will argue, from four aspects—the scientific evidence for organ autonomy, the obscuration mechanism of high-level control, the revelation of life continuity after control failure, and the reshaping of the surgical paradigm—how this new view of life provides a fundamental theoretical basis for SMIS and guides surgery towards evolving with function preservation as its core.

[1]
Chen Q, Yuan Y, Li H, et al.Chinese clinical practice guidelines for super minimally invasive surgery of digestive tract tumors[J].J Transl Int Med202513(6):487-507.
[2]
陆俊,刘凤林.《中国胃癌保功能手术外科专家共识(2025版)》更新要点解读[J].中华胃肠外科杂志202528(2) : 121-126.
[3]
令狐恩强. 胆系疾病治疗将进入零切口时代[J/OL].中华胃肠内镜电子杂志202512(2): 73.
[4]
Farber DL, Netea MG, Radbruch A, et al.Immunological memory: lessons from the past and a look to the future[J].Nat Rev Immunol, 201616(2):124-128.
[5]
Kato M, Natarajan R.Epigenetics and epigenomics in diabetic kidney disease and metabolic memory[J].Nat Rev Nephrol201915(6):327-345.
[6]
Margolis KG, Gershon MD.Enteric Neuronal Regulation of Intestinal Inflammation[J].Trends Neurosci201639(9):614-624.
[7]
Foster DS, Januszyk M, Yost KE, et al.Integrated spatial multiomics reveals fibroblast fate during tissue repair[J].Proc Natl Acad Sci USA, 2021118(41):e2110025118.
[8]
Michalopoulos GK, Bhushan B.Liver regeneration:biological and pathological mechanisms and implications[J].Nat Rev Gastroenterol Hepatol202118(1):40-55.
[9]
Jana S, Alayash AI.Exploring the Molecular Interplay Between Oxygen Transport,Cellular Oxygen Sensing,and Mitochondrial Respiration[J].Antioxid Redox Signal202542(13-15):730-750.
[10]
Sumová A, Sládek M.Circadian Disruption as a Risk Factor for Development of Cardiovascular and Metabolic Disorders - From Animal Models to Human Population[J].Physiol Res202473(Suppl1):S321-S334.
[11]
Che H, Gao Y, Xu Y, et al.Organ cross-talk:molecular mechanisms, biological functions, and therapeutic interventions for diseases[J].Signal Transduct Target Ther202611(1):8.
[12]
Zhang Z, Su J, Tang J, et al.Spinal projecting neurons in rostral ventromedial medulla co-regulate motor and sympathetic tone[J].Cell, 2024187(13):3427-3444.e21.
[13]
Lagasse E, Levin M.Future medicine: from molecular pathways to the collective intelligence of the body[J].Trends Mol Med202329(9):687-710.
[14]
Kang L, Sheng J, Bao X, et al.Establishment of the multi-organ circulatory and supervision system (MOCS)[J].Sci Bull (Beijing)2025, 70(4):488-491.
[15]
Samejima S, Shackleton C, Miller T, et al.Mapping the Iceberg of Autonomic Recovery:Mechanistic Underpinnings of Neuromodulation following Spinal Cord Injury[J].Neuroscientist202430(3):378-389.
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